His-Synchronous RV Pacing – Properly interpreting a Common Manoeuvre

Question:

28-year-old female presented with a history of palpitations lasting for hours at a time, earning her a trip to the EP Lab.

During SVT, a pacing manoeuvre was performed to differentiate the type of SVT. Given the EGM, what is the most likely SVT?

(Click to zoom on image)

Answer:

Answer:

Positive Zipes/His-Synchronous RV Pacing with AA advancement & subsequent VV perturbation indicating Accessory pathway mediated tachycardia (AVRT).

  • This tachycardia appears to visually be a mid RP tachycardia. Althought not mesured here, it measures as a short RP tachycardia, suggestive of AVJRT or AVRT.
  • The VA time appears visually >70ms, making typical slow/fast AVJRT unlikely and suggesting AVRT or atypical fast/slow AVJRT.

 

His-Synchronous RV Pacing/Zipes

Also known as “Zipes,” is a valuable maneuver for confirming the presence of accessory pathway-mediated tachycardia (AVRT). This technique is particularly useful when an accessory pathway is suspected and needs confirmation.

 

Ensuring His-Synchronicity:

Crucially, we must ensure the RV paced stimulus is “His-Synchronous,” as the maneuver is invalid otherwise.

To ensure the RV paced stimulus is “His-Synchronous” (crucial for a valid maneuver), follow these steps:

  1. Measure the preceding HH interval and the His-Stim interval.
  2. The difference between these intervals should be less than 55ms, ideally 0ms.

In the example below, H-Stim – HH interval = +10ms, so we can be fairly certain that our RV paced beat is TRULY “His Synchronous”.

Side note: I admit that our “His” signal in this example is pretty dodgy. That is no criticism of the operator; it happens to the best of them. Ideally, you have a clearer His signal than this. You’re going to have to trust me that HH measurement is really measuring a sneaky His signal.

 

What to measure?

We are interested in measuring just x2 things:

  1. The immediate AA interval (highlighted below)
  2. The Subsequent VV interval (highlighted below).

 

There are x3 possible outcomes & conclusions – many forget to differentiate the 2nd & 3rd result 

1.     No perturbation of either immediate AA interval or subsequent VV interval.

Conclusion: No evidence of Accessory pathway. NOTE: The absence of evidence is NOT evidence of absence.

 

2.     Perturbation of immediate AA interval >10ms (advancement or delay), with no change in subsequent VV interval.

Conclusion: Indicates an accessory pathway, but not its participation in tachycardia. This could suggest a bystander pathway.

 

3.     Perturbation of both immediate AA & subsequent VV interval by >10ms.

Conclusion: This confirms both the presence AND participation of the accessory pathway in tachycardia. Diagnostic of AVRT.

 

In the example above, we observe a 20ms AA Advancement, confirming the presence of an accessory pathway. Furthermore, the subsequent VV interval advances by 20ms, indicating participation in SVT.

 

My Two Cents:

This manoeuver is valuable when confirming a suspected accessory pathway.

His-synchronous RV pacing is only meaningful with a “positive” result showing AA perturbation.

No AA or VV perturbation means a null result with no meaningful interpretation. The absence of evidence is NOT evidence of absence.

Summary of results:

  1. AA perturbation: indicates an accessory pathway.
  2. VV perturbation: confirms the pathway’s participation in SVT.
  3. AA perturbation without VV perturbation: suggests a possible bystander pathway.
  4. No AA or VV perturbation: null result, no interpretation.

Due to the possibility of a “null” result, for SVT’s which appear more like AVJRT or Focal AT, RV overdrive pacing (entrainment) is probably more useful as it consistently provides useful data, irrespective of the result, so long as entrainment has been achieved.

Thanks for tuning in
Cheers
Mitch & CPP Team

 

Some extra pitfalls mentioned below :)

We have more detailed explanations on SVT differentiation manoeuvres in our EP in Practice Program 2: SVT in EP. 

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